Contraindications

Hypersensitivity to the active substance or to any of the excipients listed in section 6.1 of the Summary of Product Characteristics.

Active tuberculosis or other severe infections such as sepsis, and opportunistic infections. (see section 4.4 of the Summary of Product Characteristics).

Moderate to severe heart failure (NYHA class III/IV). (see section 4.4 of the Summary of Product Characteristics).